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We administered the Mini-Mental State Exam(MMSE)to 194 healthy men and women,ages 40 to 89 years.Total score was significantly associated with age(p<0.0001),but not vocabulary,education,Beck's Depression Inventory Score,or sex.The lowest quartile cutoff scores for the MMSE by decade were 40s-29;50s-28;60s-28;70s-28 and 80s-26.When screening for progressive decline in cognitive performance,the use of age-specific norms may provide greater sensitivity than the present recommended cutoff score of less than 24. |
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